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InChi: InChI=1S/C20H16O5/c1-10(2)3-4-11-7-14-17(9-15(11)22)25-20(23)18-13-6-5-12(21)8-16(13)24-19(14)18/h3
Tilmacoxib shows highly selective inhibition of human COX-2
splenomegaly
InChi: InChI=1S/C12H23BrO2/c1-15-12(14)10-8-6-4-2-3-5-7-9-11-13/h2-11H2
Caspase-3/7 Inhibitor I Catalog No.:M23015-C InChi: InChI=1S/C20H16O5/c1-10(2)3-4-11-7-14-17(9-15(11)22)25-20(23)18-13-6-5-12(21)8-16(13)24-19(14)18/h3Caspase 3 7 inbibitor I is a potent, reversible, isatin sulfonamide based inhibitor of caspase 3 (KI(app) = 60 nM) and caspase 7 (KI(app) = 170 nM). Is a weaker inhibitor of caspase 9 (Ki(app) = 3. 1 mM). It Has only a trivial effect (Ki(app) >25 mM) on the activities of caspase 1, caspase 2, caspase 4, caspase 6, and caspase 8. It has been shown to inhibit apoptosis in camptothecin treated Jurkat cells (IC50 ~50 M). Also it has been reported to